Jacob did not wrestle with God. It was God who wrestled with Jacob. There are times when we want something from God and we think that we can win God over. When God wrestles with us we realize as Jacob did, we are no match for Him. Instead, we wrestle with evil.
Ephesians 6:12 (ESV)
12 For we do not wrestle against flesh and blood, but against the rulers, against the authorities, against the cosmic powers over this present darkness, against the spiritual forces of evil in the heavenly places.
Yet we can find victory when we don’t wrestle in our own strength, but the strength of God.
Ephesians 6:13 (ESV)
13 Therefore take up the whole armor of God, that you may be able to withstand in the evil day, and having done all, to stand firm.